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This episode of the Summit of Greatness features renowned neuroscientist Dr. Andrew Huberman sharing science-backed strategies for improving brain function, emotional regulation, and overall wellbeing. The conversation begins with an unexpected deep dive into the neuroscience behind prayer and faith-based practices, revealing how these activities provide measurable health benefits including reduced cardiovascular disease and improved recovery from grief and addiction. (00:34) Dr. Huberman emphasizes that simply believing in a higher power isn't sufficient - it's the active engagement in faith-based practices that yields results.
Dr. Andrew Huberman is a renowned neuroscientist and professor at Stanford University who has become one of the most influential science communicators in the world. He hosts the massively popular Huberman Lab podcast and has dedicated his career to studying neuroplasticity, brain development, and human optimization. At age 50, he continues to be a practicing researcher while translating complex neuroscience into actionable protocols for peak performance and wellbeing.
Lewis Howes is the host of The School of Greatness podcast and founder of the Summit of Greatness conference. As a former professional athlete turned entrepreneur and author, he focuses on helping high achievers optimize their performance and find fulfillment. He is expecting twins and has been applying performance optimization strategies for over two decades.
Research by Dr. David Disteno at Northeastern University shows that engaging in active faith-based practices - not just believing in a higher power - yields significant health benefits including reduced cardiovascular disease, faster recovery from grief and addiction, and improved overall wellbeing. (00:20) The key distinction is between passive belief and active practice. Dr. Huberman emphasizes that these benefits come from practices that "get your mind outside itself" and acknowledge something greater than oneself, whether through prayer, communal worship, or other faith-based activities.
Cynicism is fundamentally anchored in the belief that things cannot change, making it the enemy of brain plasticity and personal growth. (13:28) In contrast, curiosity - defined as genuine interest in what might be possible coupled with the willingness to do the work to find out - is directly linked to neuroplasticity. Dr. Huberman points to great learners like Richard Feynman and Oliver Sacks who maintained curiosity about diverse subjects throughout their lives. The practical application is actively asking questions of yourself and remaining open to change rather than dismissing possibilities.
The most counterintuitive aspect of neuroplasticity is that the difficulty and errors experienced during learning are actually the signals that trigger brain change. (20:18) Recent neuroscience research shows that dopamine is released in response to errors made while trying to learn, which alerts the brain to opportunities for change. This means that frustration and struggle during the learning process should be embraced as prerequisites for growth rather than avoided. The key is maintaining alertness and focus while engaging with challenging material, understanding that the friction itself is what drives adaptation.
Revolutionary research in learning science demonstrates that reading material once followed by self-testing leads to significantly better retention after 3-6 months compared to reading the same material four times. (29:47) This principle, called "anti-forgetting," works because reflection on what was learned - including acknowledging what wasn't retained - locks information into long-term memory. Dr. Huberman emphasizes that this applies to all types of learning, from academic material to physical skills to relationship interactions. The practical application is creating deliberate reflection periods after learning sessions to test recall and identify gaps.
Rather than viewing cortisol as simply a "stress hormone," understanding its natural rhythm provides a master framework for organizing daily protocols. (47:19) Cortisol should be high in the first hour after waking and low at night, regardless of your specific wake time. Morning cortisol can be amplified through bright light exposure, exercise, caffeine (for regular users), and even grapefruit consumption. This high morning peak ensures a low evening trough, making it easier to fall asleep and stay asleep. Most protocols for optimization naturally fall into supporting this rhythm.