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Doctor Eric Topol, one of the world's most respected medical researchers, joins Mel Robbins to discuss his groundbreaking new book "SuperAgers: An Evidence Based Approach to Longevity." In this eye-opening episode, Doctor Topol reveals how environmental toxins—particularly microplastics, forever chemicals (PFAS), and air pollution—are quietly damaging our health and accelerating aging. (05:08) He explains how these substances are linked to rising cancer rates in young people, declining fertility, and various chronic diseases. Through practical demonstrations with everyday household items, he shows listeners what to look for and simple swaps they can make to reduce their toxic burden and protect their longevity.
Dr. Eric Topol is a pioneering physician scientist and cardiologist with nearly four decades of practice experience. He serves as founder and director of the Scripps Research Translational Institute and executive vice president and professor of molecular medicine at Scripps Research. Previously, he was chairman of cardiovascular medicine at Cleveland Clinic. His groundbreaking research in genomics, longevity, cardiology, precision medicine, and AI has been cited in more than 365,000 papers, making him one of the top 10 most cited medical researchers alive today. His latest book "SuperAgers" has been endorsed by five Nobel laureates.
Mel Robbins is a bestselling author, podcast host, and motivational speaker known for her practical approach to personal development and behavioral change. She hosts The Mel Robbins Podcast, where she interviews leading experts and researchers to bring science-backed insights to her global audience.
Doctor Topol reveals that microplastics are now detectable in human blood, organs, and tissues throughout the body. (09:01) A groundbreaking Italian study found that more than half of people have plastics in their carotid arteries, and those individuals have a fourfold increased risk of heart attacks and strokes. The plastics cause profound local inflammation wherever they lodge in the body, including the brain, reproductive organs, and cardiovascular system. Since these particles are non-biodegradable, they establish permanent residence once they enter our bodies.
PFAS (per- and polyfluoroalkyl substances) are synthetic chemicals found in over 10,000 different products. (13:34) Doctor Topol explains that 97% of people have detectable levels of these "forever chemicals" in their blood because they contain a fluoride-to-carbon bond that makes them non-degradable. These chemicals are linked to cancer, fertility problems, and immune system disruption. They're found in everything from hairspray and deodorant to menstrual products and non-stick cookware.
Heating plastic containers, especially in microwaves, creates a "double whammy" effect that significantly increases the release of microplastics into food. (21:33) Doctor Topol strongly advises against microwaving food in plastic containers and using non-stick cookware, as heat accelerates the transfer of toxic particles into what we consume. The longer food sits in plastic containers, the more plastic it absorbs, making storage time another critical factor.
Doctor Topol presents alarming evidence that cancer rates are rising dramatically in young people who have no genetic predisposition. (07:29) He attributes this trend to environmental toxins that are mutagenic and pro-inflammatory. Young people in their 20s are developing colon cancer and women in their early 30s are getting breast cancer at unprecedented rates. These environmental factors induce cellular mutations that can trigger cancer development.
Despite the overwhelming nature of environmental toxins, Doctor Topol emphasizes that individuals can take meaningful action to reduce their exposure. (26:37) Key changes include switching from plastic to glass containers, avoiding products with fluorinated ingredients, using wooden utensils instead of plastic ones, choosing unscented products when possible, and paying attention to product labels. While individual action has limits, these changes can meaningfully reduce the cumulative toxic burden on our bodies.