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Huberman Lab
Huberman Lab•November 27, 2025

Essentials: Using Hypnosis to Enhance Mental & Physical Health & Performance | Dr. David Spiegel

Dr. David Spiegel discusses the science and clinical applications of hypnosis, exploring how this powerful technique can enhance mental and physical health by changing brain states, reducing stress, treating trauma, managing pain, and improving focus and performance.
Mindfulness & Meditation
Mental Health Awareness
Functional Medicine
Biohacking
Andrew Huberman
David Spiegel
Gordon Bauer
Stanford University

Summary Sections

  • Podcast Summary
  • Speakers
  • Key Takeaways
  • Statistics & Facts
  • Compelling StoriesPremium
  • Thought-Provoking QuotesPremium
  • Strategies & FrameworksPremium
  • Similar StrategiesPlus
  • Additional ContextPremium
  • Key Takeaways TablePlus
  • Critical AnalysisPlus
  • Books & Articles MentionedPlus
  • Products, Tools & Software MentionedPlus
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Podcast Summary

In this Huberman Lab Essentials episode, Dr. David Spiegel, a leading authority on clinical hypnosis at Stanford, breaks down the science and practical applications of hypnosis for mental and physical health. Dr. Spiegel explains hypnosis as a state of highly focused attention that functions like "looking through the telephoto lens of consciousness" - allowing for detailed focus without peripheral distractions. (00:27)

The conversation explores how clinical hypnosis differs dramatically from stage hypnosis, with the former being about gaining control rather than losing it. (01:54) Dr. Spiegel details the specific brain networks involved, including decreased activity in the dorsal anterior cingulate cortex and increased connectivity between the dorsolateral prefrontal cortex and insula, enabling remarkable mind-body control.

• Main themes: The neuroscience of hypnosis, clinical applications for stress reduction, pain management, sleep improvement, trauma recovery, and the development of practical self-hypnosis tools for everyday use.

Speakers

Dr. David Spiegel

Dr. David Spiegel, MD, is the Associate Chair of Psychiatry & Behavioral Sciences, Director of the Center on Stress and Health, and Director of the Center for Integrative Medicine at Stanford University School of Medicine. He is a leading authority on clinical hypnosis and has conducted groundbreaking research on the therapeutic applications of hypnosis for trauma, pain management, and stress reduction.

Andrew Huberman

Andrew Huberman is a professor of neurobiology and ophthalmology at Stanford School of Medicine and host of the Huberman Lab podcast. He specializes in brain development, brain plasticity, and neural regeneration and repair, making complex neuroscience accessible to the general public through evidence-based protocols and tools.

Key Takeaways

Hypnosis Enhances Control Rather Than Removes It

Contrary to popular misconceptions influenced by stage hypnosis, clinical hypnosis actually increases your control over mind and body rather than diminishing it. (01:54) Dr. Spiegel emphasizes that "you're gaining control" and describes self-hypnosis as "a way of enhancing your control over your mind and your body." This reframe is crucial because many people avoid hypnosis thinking they'll lose autonomy, when the opposite is true. The hypnotic state allows you to consciously direct attention and regulate physiological responses that normally operate outside conscious awareness, such as gastric acid secretion and pain perception.

The Mind-Body Connection Can Be Trained and Strengthened

Through hypnosis, people can learn to control bodily functions previously thought to be automatic. (03:50) Dr. Spiegel describes a study where highly hypnotizable subjects increased gastric acid secretion by 87% just by imagining eating their favorite foods. This demonstrates that the dorsolateral prefrontal cortex can communicate through the insula to directly influence bodily functions. For professionals, this means developing greater awareness and control over stress responses, physical tension, and even immune function through structured mental practices.

Voluntary Self-Exposure to Difficult Experiences Enables Healing

The key to therapeutic breakthrough isn't avoiding difficult experiences, but rather choosing to confront them in a controlled, safe environment. (24:17) Dr. Spiegel explains that "it's not just about the state you get into, but whether or not you brought yourself there voluntarily." This principle applies beyond trauma to any challenging situation - when you deliberately engage with something difficult while maintaining a sense of agency and control, you can reframe your relationship to it and develop resilience.

Mental State Change Itself Has Therapeutic Power

Simply shifting your mental state can provide therapeutic benefits, similar to how waking up often brings clarity to problems that seemed overwhelming the night before. (11:35) Dr. Spiegel notes this principle behind the effectiveness of various treatments, from ketamine therapy to meditation. For professionals, this suggests that deliberately practicing state changes through techniques like hypnosis, breathwork, or meditation can be a powerful tool for problem-solving and emotional regulation.

Quick Assessment and Rapid Results Are Possible

Unlike many therapeutic approaches that require months of sessions, hypnosis often shows benefits immediately and can be assessed quickly. (19:08) Dr. Spiegel mentions that "two thirds of the people find that even just the one minute refresher helps them feel better" and that "you will know very quickly whether it's likely to help you or not." This makes hypnosis particularly valuable for busy professionals who need efficient, evidence-based tools they can learn and apply independently.

Statistics & Facts

  1. About one-third of adults are not hypnotizable at all, while approximately 15% are extremely hypnotizable, with the remaining two-thirds falling somewhere in between on a measurable scale from 0 to 10. (20:45) Dr. Spiegel uses this assessment to guide treatment approaches.
  2. In a study on mind-body control, highly hypnotizable subjects increased their gastric acid secretion by 87% through imagination alone, and even when injected with pentagastrin (which triggers acid release), they still achieved a 19% reduction during hypnosis. (03:50)
  3. In a pediatric study, children who used hypnosis during medical procedures had 17 minutes shorter procedure times compared to controls - a significant reduction for difficult medical procedures in young patients. (29:36)

Compelling Stories

Available with a Premium subscription

Thought-Provoking Quotes

Available with a Premium subscription

Strategies & Frameworks

Available with a Premium subscription

Similar Strategies

Available with a Plus subscription

Additional Context

Available with a Premium subscription

Key Takeaways Table

Available with a Plus subscription

Critical Analysis

Available with a Plus subscription

Books & Articles Mentioned

Available with a Plus subscription

Products, Tools & Software Mentioned

Available with a Plus subscription

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