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Huberman Lab
Huberman Lab•September 4, 2025

Essentials: Science of Mindsets for Health & Performance | Dr. Alia Crum

Dr. Alia Crum discusses how mindsets - our core beliefs about things like stress, health, and performance - can significantly impact our physiological and psychological responses. Through several groundbreaking studies, she demonstrates that our beliefs about experiences like stress, exercise, and eating can actually alter our body's physical reactions, highlighting the powerful connection between mind and body.
Mindfulness & Meditation
Mental Health Awareness
Functional Medicine
Biohacking
Andrew Huberman
Alia Crum
Carol Dweck
Peter Salovey

Summary Sections

  • Podcast Summary
  • Speakers
  • Key Takeaways
  • Compelling StoriesPremium
  • Strategies & FrameworksPremium
  • Thought-Provoking QuotesPremium
  • Statistics & Facts
  • Additional ContextPremium
  • Key Takeaways TablePlus
  • Critical AnalysisPlus
  • Similar StrategiesPlus
  • Books & Articles MentionedPlus
  • Products, Tools & Software MentionedPlus
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Podcast Summary

In this essential episode, Dr. Andrew Huberman explores groundbreaking mindset research with Stanford psychologist Dr. Alia Crum, revealing how our core beliefs about domains like stress, food, and exercise directly shape our physiological responses. Through fascinating studies—including the famous milkshake experiment (05:15) where participants' hunger hormones responded based on what they *believed* they were consuming—Dr. Crum demonstrates that mindsets act as powerful portals between conscious thought and subconscious bodily processes. The conversation delivers a revolutionary framework for leveraging stress as enhancement rather than detriment (23:54), complete with practical three-step approach: acknowledge the stress, welcome it as a signal of caring, and harness its physiological superpowers to achieve what matters most.

Speakers

Dr. Andrew Huberman (Host)

Professor of neurobiology and ophthalmology at Stanford School of Medicine, creator of the Huberman Lab podcast which has reached millions of listeners worldwide. His research focuses on neural plasticity, stress, and performance optimization.

Dr. Alia Crum

Professor at Stanford University and director of the Stanford Mind & Body Lab. Her groundbreaking research on mindset effects has been published in top-tier journals and demonstrates how beliefs about stress, food, and exercise can directly influence physiological outcomes and performance.

Key Takeaways

Reframe "Healthy" Foods as Indulgent

Your body responds physiologically to what you believe you're eating, not just the actual nutrients. When people thought they consumed a high-calorie "indulgent" milkshake, their hunger hormone ghrelin dropped threefold compared to believing it was a "diet" shake—even though both were identical. (09:03) Stop labeling nutritious foods as "sensible" or "depriving"—instead, view healthy eating as giving yourself exactly what you need to perform at your peak.

Transform Work Into Exercise

Hotel housekeepers who were told their daily work activities constituted good exercise lost weight and reduced blood pressure by 10 points within four weeks—without changing their behavior. (15:12) Audit your daily activities: walking to meetings, taking stairs, even carrying groceries can become "workouts" when you consciously recognize them as beneficial physical activity.

Welcome Stress as Your Performance Ally

Adopt a three-step approach: acknowledge you're stressed, welcome it as a sign you care deeply about something meaningful, then channel that stress response to achieve your goal rather than eliminate it. (34:15) The stress response narrows focus, speeds information processing, and can trigger anabolic hormone release—treat it as a superpower, not a liability.

Challenge Your Core Assumptions

Mindsets are simplifying belief systems about domains like intelligence, food, or stress that shape expectations and guide behavior. (00:40) Regularly audit your default assumptions: Do you believe abilities are fixed or malleable? Is stress enhancing or debilitating? These core beliefs become self-fulfilling prophecies that influence both motivation and physiology.

Leverage Belief Effects in Medicine

When patients view side effects as evidence their treatment is working (rather than harmful), outcomes improve significantly. (37:38) Apply this beyond healthcare: frame temporary discomfort during skill acquisition as proof of neural rewiring, or muscle soreness as confirmation of strength gains—your interpretation shapes your physiological response.

Compelling Stories

Available with a Premium subscription

Strategies & Frameworks

Available with a Premium subscription

Thought-Provoking Quotes

Available with a Premium subscription

Statistics & Facts

No specific statistics were provided in this episode.

Additional Context

Available with a Premium subscription

Key Takeaways Table

Available with a Plus subscription

Critical Analysis

Available with a Plus subscription

Similar Strategies

Available with a Plus subscription

Books & Articles Mentioned

Available with a Plus subscription

Products, Tools & Software Mentioned

Available with a Plus subscription

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