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In this comprehensive episode, Dr. Andrew Huberman sits down with Dr. Brett Contreras, the renowned "Glute Guy" and sports science expert, to explore the science and practice of resistance training. (02:15) Dr. Contreras shares his three decades of experience training clients, from everyday people to elite athletes, revealing how to build effective resistance training programs tailored to specific aesthetic and performance goals.
Dr. Brett Contreras holds a doctorate degree in sports science and is a certified strength and conditioning specialist with over three decades of experience in resistance training. Known worldwide as "the Glute Guy," he pioneered hip thrust exercises and specialized glute training methods that have transformed how people approach lower body development. He has trained thousands of clients and is considered one of the most trusted voices in the fitness industry due to his unique combination of scientific credentials and proven real-world results.
Dr. Andrew Huberman is a professor of neurobiology and ophthalmology at Stanford School of Medicine. He hosts the Huberman Lab Podcast, where he translates complex neuroscience and health research into practical tools for everyday life. With over 33 years of resistance training experience starting at age 16, Dr. Huberman brings both scientific rigor and personal experience to discussions about optimizing human performance and health.
The fundamental principle of muscle growth is progressive overload - placing increasing tension on muscles over time. (06:06) However, Dr. Contreras emphasizes that this doesn't mean you must add weight or reps every single workout indefinitely. Instead, focus on gaining strength over 3-4 week periods, then switch exercises or movement patterns. This prevents injury while maintaining continuous adaptation. The key is tracking progress in a logbook and having specific goals for each workout, rather than just going through the motions.
Your optimal training frequency depends on your Maximum Recoverable Volume - the most work you can do while still recovering properly. (31:57) For beginners, 2-3 full-body workouts per week typically work best. More experienced lifters might benefit from training each muscle group 2-3 times per week, but must carefully manage exercise selection and intensity. The goal is to do as much productive volume as possible without compromising recovery, which varies greatly between individuals based on genetics, sleep, stress, and other factors.
To bring up lagging body parts, increase volume and frequency for that muscle group while reducing volume for other areas. (130:30) Dr. Contreras recommends focusing on 1-2 body parts per training block (4-6 weeks), doing maintenance work for other muscles. This approach leverages the fact that it's much easier to maintain muscle and strength than to build it initially. For glutes specifically, training 3 times per week using different movement patterns (vertical, horizontal, and lateral vectors) can accelerate development.
Different exercises create varying amounts of muscle damage and fatigue. (25:00) When training frequently, choose exercises that allow better recovery. For example, step-ups may be preferable to walking lunges when training legs three times per week, as lunges can create excessive soreness. Hip thrusts work muscles in a shortened position and create less damage than squats, allowing for higher training frequency. Understanding these differences helps optimize your exercise selection for your training goals and recovery capacity.
Developing the ability to consciously contract target muscles amplifies training effectiveness. (37:57) Dr. Contreras recommends practicing muscle contractions without weights first - if you can't flex a muscle voluntarily, you can't effectively train it against resistance. This neuromuscular skill becomes increasingly important as you advance, allowing you to generate more force and better target specific muscles. The combination of external progression (more weight/reps) and internal focus (mind-muscle connection) provides the optimal stimulus for long-term growth.