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Sam and Shaan answer listener questions about business, personal experiences, and potential career paths, offering insights on hiring, investing, and life strategies while sharing personal anecdotes and advice.
Lightspeed partner Michael Mignano discusses his investment strategy in AI and creativity, highlighting investments in companies like xAI, Neuralink, Suno, and Pika, while exploring the evolving landscape of technology, media, and creator economics.
Michael Mignano, co-founder of Anchor and now a partner at Lightspeed Ventures, discusses how AI is transforming consumer startups by making previously "impossible" ideas accessible, with insights on media, distribution, and the future of creative tools.
A thought-provoking exploration of the U.S. government's Genesis Mission, AI advancements from Anthropic and other tech giants, and the potential societal transformations driven by artificial intelligence and emerging technologies.
Philip Clark of Thrive Capital discusses the firm's concentrated investment strategy across groundbreaking companies like OpenAI, Cursor, Wiz, Nudge, and Physical Intelligence, highlighting their focus on transformative technologies in AI, hardware, and emerging domains like brain engineering.
An interview with Lada Nuzhna, founder of General Control, exploring her journey in biotech, the challenges of developing aging therapies, and her mission to engineer epigenetic medicines that could potentially extend human lifespan.
Ashlee Vance discusses his experiences interviewing tech luminaries like Elon Musk, Brian Johnson, and Palmer Luckey, sharing insights into their personalities, work ethic, and the challenges of covering complex technological frontiers like quantum computing and fusion. He reflects on his journalistic career, highlighting the persistent and focused nature of innovators, and teases upcoming projects for his podcast Core Memory.
Edward Chang discusses groundbreaking advancements in neurosurgery, focusing on brain-computer interfaces that can restore speech for patients with paralysis, such as Anne, who suffered a brainstem stroke. The conversation explores how technology and neuroscience are converging to decode brain signals, potentially transforming the treatment of neurological conditions like ALS, stroke, and glioblastoma.
Two pioneering neurotechnology experts discuss brain computer interfaces (BCIs) that can decode brain signals non-invasively, with potential applications ranging from helping paralyzed patients communicate to understanding consciousness states like comas. The podcast explores how these advanced BCIs could revolutionize interactions between human brains and digital technologies, offering glimpses into future medical treatments and potentially merging human cognition with artificial intelligence.