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No Priors: Artificial Intelligence | Technology | Startups
No Priors: Artificial Intelligence | Technology | Startups•December 19, 2025

The 2026 AI Forecast: Foundation Models, IPOs, and Robotics with Sarah Guo and Elad Gil

In this episode, Sarah Guo and Elad Gil discuss their predictions for 2026, focusing on AI trends including foundation models, robotics, self-driving technologies, IPOs, consumer AI innovation, and the potential breakthroughs in various industries like defense, healthcare, and drug discovery.
AI & Machine Learning
Tech Policy & Ethics
Developer Culture
Robotics
Web3 & Crypto
Jensen Huang
Ilya Sutskever
Bryan Johnson

Summary Sections

  • Podcast Summary
  • Speakers
  • Key Takeaways
  • Statistics & Facts
  • Compelling StoriesPremium
  • Thought-Provoking QuotesPremium
  • Strategies & FrameworksPremium
  • Similar StrategiesPlus
  • Additional ContextPremium
  • Key Takeaways TablePlus
  • Critical AnalysisPlus
  • Books & Articles MentionedPlus
  • Products, Tools & Software MentionedPlus
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Timestamps are as accurate as they can be but may be slightly off. We encourage you to listen to the full context.

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Podcast Summary

In this year-end episode of No Priors, hosts Sarah Guo and Elad Gil examine the rapidly evolving AI landscape and share their bold predictions for 2026. (02:43) They explore how AI adoption is accelerating in traditionally conservative professions like medicine and law, despite ongoing debates about market bubbles. The hosts discuss the future of robotics and autonomous vehicles, analyzing whether incumbents like Tesla and Google will dominate or if startups can compete. (13:59) They predict a surge in AI company IPOs and examine why consumer AI innovation has lagged behind enterprise adoption. The episode concludes with predictions from tech leaders including Jensen Huang, Aaron Levie, and others on what 2026 will bring for AI and beyond.

  • Main Theme: The maturation of AI from experimental technology to mainstream adoption, with 2026 poised to be a pivotal year for enterprise deployment, consumer breakthroughs, and market dynamics.

Speakers

Sarah Guo

Sarah Guo is a prominent venture capitalist and co-host of the No Priors podcast, focusing on AI and technology investments. She has extensive experience evaluating and funding AI startups across various sectors and is known for her insights into enterprise AI adoption and consumer product development.

Elad Gil

Elad Gil is a serial entrepreneur, investor, and technology executive who has been involved with companies like Twitter, Google, and Airbnb. He is co-host of No Priors and has extensive experience in scaling technology companies and understanding market dynamics in emerging tech sectors.

Key Takeaways

Conservative Professions Are Leading AI Adoption

Contrary to typical technology adoption patterns, traditionally slow-to-adopt professions like physicians, lawyers, and accountants are embracing AI at unprecedented speeds. (04:42) Sarah highlighted that doctors are showing "massive enthusiasm" for AI tools like clinical decision support and documentation systems. This represents a fundamental shift where the people who "always never adopt technology are now adopting this stuff fast." The reason is clear: AI directly addresses their core workflow challenges around reasoning with unstructured data, making their work significantly more efficient and effective.

Robotics Will Face Reality Checks Despite Long-Term Promise

While robotics and autonomous systems will make meaningful progress in 2026, Elad predicts "some collapse of sentiment around a set of robotics companies" as projected timelines meet reality. (07:18) The comparison to self-driving cars is instructive - despite taking longer than expected, companies like Waymo and Tesla are now seeing real success. The key insight is that robotics will likely follow a similar pattern where incumbents with existing supply chains, manufacturing capabilities, and sensor expertise (like Tesla with Optimus) may have structural advantages over pure-play startups, though breakthrough opportunities still exist.

Foundation Models Will Expand Beyond Language to Transform Science

The next generation of foundation models will tackle physics, materials science, and mathematics, potentially leading to breakthrough discoveries. (06:32) Elad predicts we'll see "one or two use cases where it works really well for something - they'll invent some new material, or there'll be some conjecture proved." This will initially create overhyped expectations about AI solving all of science, but the long-term trend toward AI-powered scientific discovery will be "incredibly important." These domain-specific models represent the next frontier beyond language understanding.

Consumer AI Innovation Will Finally Break Through

After years of disappointing consumer AI products, 2026 will mark the emergence of compelling consumer agent software that people actually want to use. (16:47) Sarah noted she's seeing "magical experiences" from stealth companies building truly different consumer applications. The key insight is that early attempts focused on "building better versions of last generation experiences with this generation technology," which wasn't compelling. Success requires being "quite close to research or pretty creatively ambitious" to build something genuinely different rather than incremental improvements.

AI IPOs Will Drive Market Dynamics and Retail Participation

The AI sector will see a significant wave of IPOs in 2026, driven by enormous retail appetite to participate in the AI revolution beyond just NVIDIA. (16:15) Elad predicts that "if one of the main AI companies goes out, it'll probably do extremely well" and will trigger followers to go public as well. A hedge fund manager's strategy reveals the market dynamics: regardless of fundamental analysis, institutional investors feel compelled to buy AI IPOs because retail demand will drive performance, creating a self-reinforcing cycle of investment and public market participation.

Statistics & Facts

  1. No specific statistics were provided in this episode. The hosts focused on qualitative trends and predictions rather than quantitative data points.

Compelling Stories

Available with a Premium subscription

Thought-Provoking Quotes

Available with a Premium subscription

Strategies & Frameworks

Available with a Premium subscription

Similar Strategies

Available with a Plus subscription

Additional Context

Available with a Premium subscription

Key Takeaways Table

Available with a Plus subscription

Critical Analysis

Available with a Plus subscription

Books & Articles Mentioned

Available with a Plus subscription

Products, Tools & Software Mentioned

Available with a Plus subscription

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