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Monetary Matters with Jack Farley
Monetary Matters with Jack Farley•December 29, 2025

Investing in Gray | Pictet’s Maria Vassalou on Aging Demographics and Technological Innovations

Maria Vassalou from Pictet Research Institute discusses how aging global demographics threaten economic growth, but technological innovations in robotics and AI can mitigate these challenges by enhancing productivity and replacing scarce labor across sectors like housing, healthcare, and food.
Corporate Strategy
Venture Capital
AI & Machine Learning
Jack Farley
Maria Vassalou
Goldman Sachs
United Nations
Pictet Research Institute

Summary Sections

  • Podcast Summary
  • Speakers
  • Key Takeaways
  • Statistics & Facts
  • Compelling StoriesPremium
  • Thought-Provoking QuotesPremium
  • Strategies & FrameworksPremium
  • Similar StrategiesPlus
  • Additional ContextPremium
  • Key Takeaways TablePlus
  • Critical AnalysisPlus
  • Books & Articles MentionedPlus
  • Products, Tools & Software MentionedPlus
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Podcast Summary

In this episode of Monetary Matters, host Jack Farley sits down with Maria Vassalou, head of the Pictet Research Institute, to explore one of the most significant economic trends of our time: global demographic decline and its intersection with technological revolution. (00:37) Unlike typical economic forecasts, demographic projections offer rare certainty in macroeconomics, as birth rates and population aging follow predictable patterns decades into the future. (02:45) The conversation reveals that dependency ratios in developed countries will exceed 50% over the next 20-30 years, with countries like Japan potentially reaching 73% and Italy 70%. (03:45) However, rather than painting a doom-and-gloom picture, Vassalou argues that the rise of robotics and AI provides a critical remedy by substituting scarce labor and boosting productivity. (04:56) The discussion concludes by identifying housing, healthcare, and food as resilient sectors poised for growth, while emphasizing that countries must invest heavily in technology now to avoid long-term economic stagnation.

  • Main Theme: The intersection of global demographic decline and technological advancement as both challenge and solution for future economic growth.

Speakers

Jack Farley

Host of Monetary Matters, Jack Farley conducts in-depth interviews on macroeconomic trends and financial markets. He brings expertise in analyzing complex economic phenomena and translating them for professional audiences seeking actionable insights.

Maria Vassalou

Head of the Pictet Research Institute, Maria Vassalou brings extensive experience from her senior role at Goldman Sachs in investing. She holds a PhD and leads research on critical economic trends, with particular expertise in demographics and technology intersection. Her work focuses on long-term economic projections and the role of technological innovation in addressing demographic challenges.

Key Takeaways

Technology Must Replace Declining Labor Force

With dependency ratios projected to exceed 50% in most developed countries over the next 20-30 years, traditional economic models face fundamental disruption. (05:00) As Vassalou explains, when labor becomes scarce due to demographic decline, the production function requires substitution through technology. The remedy lies in robotics and AI that can directly replace labor while making existing workers far more productive. This isn't just about cost reduction—it's about economic survival as entire societies age and shrink.

Infrastructure and Materials Investments Offer Greatest Returns

Rather than chasing trendy AI applications, smart investors should focus on the foundational elements powering technological transformation. (46:06) Vassalou emphasizes infrastructure around AI usage, materials used in AI processes, and various forms of energy that fuel these technologies. The focus should be on enabling infrastructure and applications in sectors driving bulk consumption in aging societies, particularly in Europe where productivity rates have been historically low.

Manufacturing Productivity Gains Trump Services

While services dominate developed economies, manufacturing offers twice the productivity potential of services sectors. (51:15) Vassalou's research shows that even with AI applications in services, the most significant economic impact comes from manufacturing improvements. Countries must prioritize automation in housing materials, food processing, and healthcare equipment production—sectors that aging populations will demand more heavily.

Immigration Cannot Solve Global Demographics

The demographic crisis is fundamentally global, not localized, making immigration a zero-sum solution. (65:42) As Vassalou points out, moving people from high-fertility to low-fertility regions doesn't increase global labor availability—it's "creative accounting" that temporarily shifts the problem without solving it. Countries that have invested in productivity and technology rather than relying heavily on immigration are better positioned for long-term growth and living standard maintenance.

Winners and Losers Are Already Determined

Economic sectors will diverge dramatically based on aging population consumption patterns and automation potential. (24:03) Housing, healthcare, and food emerge as clear winners due to increased demand from older populations and high automation potential. Transport and clothing face headwinds as aging consumers reduce spending in these categories. Success depends on three factors: sector conduciveness to automation, demographic demand trends, and institutional support for technology implementation.

Statistics & Facts

  1. By 2050, China's elderly dependency ratio (population 65+ relative to working age 15-64) will increase from 21% to 52%, with projections showing it could exceed 100% by 2080, meaning more seniors than working-age adults. (04:14)
  2. In Japan, the dependency ratio could reach as high as 73%, while Italy is projected to reach 70%, representing the most acute demographic challenges globally. (03:50)
  3. Productivity in the manufacturing sector is approximately twice as high as in services, making technology investments in manufacturing far more impactful for economic growth than similar investments in services. (51:15)

Compelling Stories

Available with a Premium subscription

Thought-Provoking Quotes

Available with a Premium subscription

Strategies & Frameworks

Available with a Premium subscription

Similar Strategies

Available with a Plus subscription

Additional Context

Available with a Premium subscription

Key Takeaways Table

Available with a Plus subscription

Critical Analysis

Available with a Plus subscription

Books & Articles Mentioned

Available with a Plus subscription

Products, Tools & Software Mentioned

Available with a Plus subscription

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