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In this fascinating episode, comedian and science communicator Sarah Rose Siskind explores the intersection of AI and creativity while conducting an unusual experiment: training an LLM called "FetusGPT" exclusively on sounds her unborn baby hears in utero. (02:03) The conversation dives deep into how AI can serve as both a creative collaborator and emotional support system, with Siskind sharing how she uses ChatGPT in her comedy writing process and for navigating pregnancy challenges.
Sarah Rose Siskind is a professional comedian, science comedy writer, and founder of the science and technology communications agency Hello SciCom. She specializes in using humor to make science and technology more accessible, and has become an advocate for AI as a creative tool. Currently pregnant, she's conducting the unique FetusGPT experiment to explore AI training methodologies.
Dan Shipper is a technology entrepreneur, writer, and host of the AI & I podcast. He's a University of Pennsylvania alumnus who has built and sold companies, and is known for his thoughtful analysis of AI's impact on creativity and business.
Siskind emphasizes that AI works best when used as part of a creative process rather than expecting it to generate perfect output immediately. (15:32) She explains that professional comedians shouldn't expect AI to tell perfect jokes any more than they'd expect a stranger to instantly make them laugh. The key is iteration and understanding AI's role in the creative workflow.
Drawing from Wharton research, Siskind outlines a two-phase creative process: divergent thinking (brainstorming phase where AI helps generate diverse ideas) and convergent thinking (research and refinement phase where AI assists with wordsmithing and editing). (17:21) This structured approach maximizes AI's effectiveness in creative work.
Beyond practical applications, AI can serve as an emotional support system, particularly during challenging life experiences. (66:05) Siskind describes how ChatGPT provided sophisticated emotional intelligence during her pregnancy concerns, accurately predicting and validating her fears before providing reassurance, which made her more receptive to the guidance.
Siskind used AI combined with continuous glucose monitoring to optimize her energy levels and understand her body's patterns. (44:15) This biohacking approach helped her discover that she needed healthy sugars in the morning to combat hypoglycemia, transforming her from someone who thought she wasn't a morning person to someone who could be productive early in the day.
One of AI's unique capabilities is answering questions that couldn't be asked before, such as asking an AI to "forget" certain knowledge and analyze patterns. (57:11) Siskind demonstrated this by asking AI to analyze gender differences in historical writing while pretending not to know about gender categories, revealing interesting patterns about integration vs. specialization approaches.